Publication list (Paper in English)
2012
54
The interaction and integration of auxin signaling components.
Hayashi K*.
Plant Cell Physiol. 2012 [Review paper]. PMID:2243345
53
A Chemical Biology Approach Reveals an Opposite Action between Thermospermine and Auxin in Xylem Development in Arabidopsis thaliana.
Yoshimoto K, Noutoshi Y, Hayashi K, Shirasu K, Takahashi T, Motose H.
Plant Cell Physiol. 2012 [PubMed - as supplied by publisher]
52
Rational Design of an Auxin Antagonist of the SCF(TIR1) Auxin Receptor Complex.
Hayashi K*, Neve J, Hirose M, Kuboki A, Shimada Y, Kepinski S, Nozaki H.
ACS Chem Biol. 2012 16, 90-8.
2011
51
Transcription of DWARF4 Plays a Crucial Role in Auxin-Regulated Root Elongation in Addition to Brassinosteroid Homeostasis in Arabidopsis thaliana.
Y. Yoshimitsu, K. Tanaka, W. Fukuda, T. Asami, S. Yoshida, K. Hayashi, Y. Kamiya, Y. Jikumaru, T. Shigeta, Y. Nakamura, T. Matsuo, S. Okamoto
PLoS. One., 2011, 6, e23851
50
Alkoxyauxins are selective inhibitors of auxin transport mediated by PIN, ABCB, and AUX1 transporters.
E. Tsuda, H. Yang, T. Nishimura, Y. Uehara, T. Sakai, M. Furutani, T. Koshiba, M. Hirose, H. Nozaki, A.S. Murphy, K. Hayashi *
J. Biol. Chem., 2011, 286, 2354-2364
49
Enzymatic 13C-labeling and multidimensional NMR analysis of miltiradiene synthesized by a bifunctional diterpene cyclase in Selaginella moellendorffii..
Y Sugai, Y Ueno, KI Hayashi, S Oogami, T Toyomasu, S Matsumoto, M Natsume, H Nozaki, H Kawaide
J Biol Chem, 2011, 286, 42840-7
48
The main auxin biosynthesis pathway in Arabidopsis..
K Mashiguchi, K Tanaka, T Sakai, S Sugawara, H Kawaide, M Natsume, A Hanada, T Yaeno, K Shirasu, H Yao, P McSteen, Y Zhao, K Hayashi, Y Kamiya, H Kasahara
Proc Natl Acad Sci U S A, 2011, 108, 18512-18517
47
Using the pER8:GUS Reporter System to Screen for Phytoestrogens from Caesalpinia sappan.
W.C. Lai, H.C. Wang, G.Y. Chen, J.C. Yang, M. Korinek, C.J. Hsieh, H. Nozaki, K. Hayashi, C.C. Wu, Y.C. Wu, F.R. Chang
J. Nat. Prod., 2011, 74, 1698-1706
46
Identification of the single amino acid involved in quenching the ent-kauranyl cation by a water molecule in ent-kaurene synthase of Physcomitrella patens.
H. Kawaide, K. Hayashi, R. Kawanabe, Y. Sakigi, A. Matsuo, M. Natsume, H. Nozaki
FEBS. J., 2011, 278, 123-133
2010
45
Endogenous diterpenes derived from entkaurene, a common gibberellin precursor, regulate protonema differentiation of the moss Physcomitrella patens.
K. Hayashi*, K. Horie, Y. Hiwatashi, H. Kawaide, S. Yamaguchi, A. Hanada, T. Nakashima, M. Nakajima, L.N. Mander, H. Yamane, M. Hasebe, H. Nozaki
Plant. Physiol., 2010, 153, 1085-1097
44
ABP1 mediates auxin inhibition of clathrin-dependent endocytosis in Arabidopsis. S. Robert, J. Kleine-Vehn, E. Barbez, M. Sauer, T. Paciorek, P. Baster, S. Vanneste, J. Zhang, S. Simon, M. Covanova,
K. Hayashi, P. Dhonukshe, Z. Yang, S.Y. Bednarek, A.M. Jones, C. Luschnig, F. Aniento, E. Zazimalova, J. Friml
Cell., 2010, 143, 111-121
43
Scavenging effects of metal complexes of water-soluble thiacalix[4]arenetetrasulfonate on superoxide anion radicals.
J. Odo, A. Kimura, A. Matsu-Ura, Y. Ohnishi, Y. Saeki, A. Yoshida, K. Hayashi, M. Inoguchi, T. Ueki
Chem. Pharm. Bull. (Tokyo.), 2010, 58, 1576-1581
2009
42
Kusaka N, Maisch J, Nick P, Hayashi KI*, Nozaki H.
Manipulation of Intracellular Auxin in a Single Cell by Light with Esterase-Resistant Caged Auxins.
Chembiochem. 2009, 10(13):2195-2202. ( Cover Picture and highlightend in Nature Chamical Biology)
41
Kamei Y, Sueyoshi M, Hayashi K, Terada R, Nozaki H.
The novel anti-Propionibacterium acnes compound, Sargafuran, found in the marine brown alga Sargassum macrocarpum.
J Antibiotics 2009 Mar 27 in press
40
Hayashi K*, Kamio S, Oono Y, Townsend LB, Nozaki H.
Toyocamycin specifically inhibits auxin signaling mediated by SCFTIR1 pathway.
Phytochemistry. 2009 Jan;70(2):190-7
2008
39
K. Hayashi*, A. Yamazoe, Y. Ishibashi, N. Kusaka, Y. Oono, and H.Nozaki
Active Core Structure of Terfestatin A, a New Specific Inhibitor of Auxin Signaling .
Bioorg. Med. Chem., 2008, 16(9):5331-44.
38
K. Hayashi*, X. Tan, N. Zheng, T. Hatate, Y. Kimura, S. Kepinski, H. Nozaki
Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling
Proc Natl Acad Sci U S A, 2008, 105(14) 5632-5637
2007
37
Nozaki H, Hayashi K, Nishimura N, Kawaide H, Matsuo A, Takaoka D.
Momilactone A and B as allelochemicals from moss Hypnum plumaeforme: first occurrence in bryophytes
Biosci Biotechnol Biochem. 2007,71(12):3127-30 36
36
Nozaki H, Hayashi K, Kido M, Kakumoto K, Ikeda S, Matsuura N, Tani T, Takaoka D, Iinuma M and Akao Y
Pauferrol A, a novel chalcone trimer with a cyclobutane ring from Caesalpinia ferrea mart exhibiting DNA
topoisomerase II inhibition and apoptosis-inducing activity.
Tetrahedron Letters, 2007, 48(47): 8290-8292
35
H. Nozaki, K. Hayashi, K. Okuda, F. Kuyama, K. Ono, N. Nishimura, A. Matsuo
Ent-kaurane-type diterpenoids from a cell suspension culture of the liverwort
Jungermannia subulata,
Planta Medica, 2007, 73(7):689-9
34
Ina A, HayashiK, NozakiH, Kamei Y
Pheophytin a,a low molecular weight compound found in the marine brown
alga Sargassum fulvellum, promotes the differentiation of PC12 cells.
Int. J. Devl. Neurosci., 2007, 25(1):63-8 .
2006
33
Hayashi K, Kawaide H, Notomi M, Sakigi Y, Matsuo A, and Nozaki H
Identification and functional analysis of bifunctional ent-kaurene synthase from the moss Physcomitrella patens
FEBS Lett. 2006, 13;580(26):6175-81.
32
31
M Yamada, K Hayashi, H Hayashi, R Tsuji, K Kakumoto, S Ikeda, T Hoshino, K Tsutsui, K Tsutsui, T Ito, M Iinuma, H Nozaki
Nepalensinols D–G, New Resveratrol Oligomers from Kobresia nepalensis (Cyperaceae) as Potent Inhibitors of DNA Topoisomerase II
Chem Pharm Bull. 2006 Mar;54(3):354-8.
30
K Hayashi, K Hashimoto, N Kusaka, A Yamazoe, H Fukaki, M Tasaka, andH Nozaki
Caged Gene-Inducer Spatially and Temporally Controls Gene Expression and Plant Development in Transgenic Arabidopsis Plant
Bioorg Med Chem Lett. 2006 May 1;16(9):2470-4
29
Chang FR, Chen IH, Liao SC, Issa HH, Hayashi K, Nozaki H, Wu YC, Lee KH.
Three New Agarofuran Sesquiterpenes Reissantins F - H from Reissantia buchananii.
Planta Med. 2006 Jan;72(1):92-6.
28
Yamada M, Hayashi K, Hayashi H, Ikeda S, Hoshino T, Tsutsui K, Tsutsui K, Iinuma M, Nozaki H
Stilbenoids of Kobresia nepalensis (Cyperaceae) exhibiting DNA topoisomerase II inhibition.
Phytochemistry. 2006 Feb;67(3):307-13
27
Nakamura A, Nakajima N, Goda H, Shimada Y, Hayashi K, Nozaki H, Asami T, Yoshida S, Fujioka S
Arabidopsis Aux/IAA genes are involved in brassinosteroid-mediated growth responses in a manner dependent on organ type.
Plant J. 2006 Jan 45(2):193-205
2005
26
Atsushi Yamazoe, Ken-ichiro Hayashi, Stefan Kepinski, Ottoline Leyser, and Hiroshi Nozaki
Characterization of Terfestatin A, a New Specific Inhibitor for Auxin Signaling
Plant Physiology 2005 139:779-789.
25
Fang-Rong Chang, Ken-ichiro Hayashi, Nam-Hai Chua, Shuichi Kamio, Zih-You Huang, Hiroshi Nozaki, Yang-Chang Wu
Transgenic Arabidopsis plant, pER8-GFP, as a Powerful Tool in Searching Natural Estrogen-agonist/antagonists
Journal of Natural Products 2005 Jul;68(7):971-3.
24
Ken-ichiro Hayashi, Takashi Kanamori, Atsushi Yamazoe, Masashi Yamada and Hiroshi Nozaki
Gaudichanolides A and B, two new ent-clerodane diterpenes from Baccharis gaudichaudiana DC.
Journal of Natural Products 2005 Jul;68(7):1121-4.
23
Dai, Xinhua; Hayashi, Ken-ichiro; Nozaki, Hiroshi; Cheng, Youfa; Zhao, Yunde.
Genetic and chemical analyses of the action mechanisms of sirtinol in Arabidopsis.
Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):3129-34
2004
22
Liaw, Chih-Chuang; Chang, Fang-Rong; Wu, Chin-Chung; Chen, Shu-Li; Bastow, Kenneth F.; Hayashi, Ken-ichiro; Nozaki, Hiroshi ; Lee, Kuo-Hsiung; Wu, Yang-Chang. Nine new cytotoxic monotetrahydrofuranic annonaceous acetogenins from Annona montana.
Planta Medica (2004), 70(10), 948-959.
21
Yamazoe, Atsushi; Hayashi, Ken-Ichiro; Kuboki, Atsuhito; Ohira, Susumu; Nozaki, Hiroshi.
The isolation, structural determination, and total synthesis of terfestatin A, a novel auxin signaling inhibitor from Streptomyces sp.
Tetrahedron Letters (2004), 45(45), 8359-8362.
20
Kodama, M.; Abe, M.; Kawasaki, Y.; Hayashi, K.; Ohira, S.; Nozaki, H.; Katagiri, C.; Inoue, K.; Takahashi, H.
Estimation of interlamellar water molecules in sphingomyelin bilayer systems studied by DSC and x-ray diffraction.
Thermochimica Acta (2004), 416(1-2), 105-111.
19
Hayashi, Ken-Ichiro; Chang, Fang-Rong; Nakanishi, Yuka; Bastow, Kenneth F.; Cragg, Gordon; McPhail, Andrew T.; Nozaki, Hiroshi ; Lee, Kuo-Hsiung. Antitumor Agents. 233.Lantalucratins A-F, New Cytotoxic Naphthoquinones from Lantana involucrata.
Journal of Natural Products (2004), 67(6), 990-993.
2003
18
Oono, Yutaka; Ooura, Chiharu; Rahman, Abidur; Aspuria, Evalour T.; Hayashi, Ken-ichiro; Tanaka, Atsushi; Uchimiya, Hirofumi.
p-Chlorophenoxyisobutyric acid impairs auxin response in Arabidopsis root.
Plant Physiology (2003), 133(3), 1135-1147.
17
Chang, Fang-Rong; Hayashi, Ken-Ichiro; Chen, I-Hsiao; Liaw, Chih-Chuang; Bastow, Kenneth F.; Nakanishi, Yuka; Nozaki, Hiroshi ; Cragg, Gordon M.; Wu, Yang-Chang; Lee, Kuo-Hsiung.
Antitumor Agents. 228. Five New Agarofurans, Reissantins A-E, and Cytotoxic Principles from Reissantia buchananii.
Journal of Natural Products (2003), 66(11), 1416-1420.
16
Hayashi, Ken-Ichiro; Jones, Alan M.; Ogino, Kentaro; Yamazoe, Atsushi; Oono, Yutaka; Inoguchi, Masahiko; Kondo, Hirokiyo; Nozaki, Hiroshi.
Yokonolide B, a Novel Inhibitor of Auxin Action, Blocks Degradation of AUX/IAA Factors.
Journal of Biological Chemistry (2003), 278(26), 23797-23806.
15
Wu, Jiu-Hong; Chang, Fang-Rong; Hayashi, Ken-ichiro; Shiraki, Hiroaki; Liaw, Chih-Chuang; Nakanishi, Yuka; Bastow, Kenneth F.; Yu, Donglei; Chen, Ih-Sheng; Lee, Kuo-Hsiung.
Antitumor agents. Part 218: Cappamensin A, a new In vitro anticancer principle, from Capparis sikkimensis.
Bioorganic & Medicinal Chemistry Letters (2003), 13(13), 2223-2225.
14
Hayashi, Ken-ichiro; Nakanishi, Yuka; Bastow, Kenneth F.; Cragg, Gordon; Nozaki, Hiroshi; Lee, Kuo-Hsiung.
Antitumor Agents. 221. Buceracidins A and B, Two New Flavanones from Bucida buceras.
Journal of Natural Products (2003), 66(1), 125-127.
2000- 2002
13
Hayashi, Ken-ichiro; Nakanishi, Yuka; Bastow, Kenneth F.; Cragg, Gordon; Nozaki, Hiroshi; Lee, Kuo-Hsiung.
Antitumor agents. Part 212 Bucidarasins A-C, three new cytotoxic clerodane diterpenes from Bucida buceras.
Bioorganic & Medicinal Chemistry Letters (2002), 12(3), 345-348.
12
Hayashi, Ken-Ichiro; Ogino, Kentaro; Oono, Yutaka; Uchimiya, Hirofumi; Nozaki, Hiroshi.
Yokonolide A, a new inhibitor of auxin signal transduction, from Streptomyces diastatochromogenes B59.
Journal of Antibiotics (2001), 54(7), 573-581.
11
Hayashi, K.-i.; Inoguchi, M.; Kondo, H.; Nozaki, H .
Gibbestatin B inhibits the GA-induced expression of a-amylase expression in cereal seeds.
Phytochemistry (2000), 55(1), 1-9.
1998- 1999
10
Hayashi, Ken-Ichiro; Nozaki, Hiroshi .
Isolation and characterization of gibbestatin B, an inhibitor of gibberellin-induced expression of a-amylase, and gibbestatin C from streptomycetaes.
Journal of Antibiotics (1999), 52(10), 917-920.
9
Hayashi, Ken-Ichiro; Nozaki, Hiroshi .
Kitamycins, new antimycin antibiotics produced by Streptomyces sp.
Journal of Antibiotics (1999), 52(3), 325-328.
8
Hayashi, Ken-Ichiro; Asano, Ken-Ichi; Tanaka, Mitsuo; Takaoka, Daisuke; Nozaki, Hiroshi .
Biotransformation of shiromodiol diacetate, myli-4(15)-en-9-one and myliol by Aspergillus niger.
Phytochemistry (1998), 48(3), 461-466.
7
Ohira, Susumu; Hasegawa, Taisuke; Hayashi, Ken-Ichiro; Hoshino, Takuji; Takaoka, Daisuke; Nozaki, Hiroshi .
Sesquiterpenoids from Cyperus rotundus.
Phytochemistry (1998), 47(8), 1577-1581.
～1995
6
Hayashi, Ken-ichiro; Dombou, Munehiko; Sekiya, Michie; Nakajima, Hiroshi.
Thermorubin and 2-hydroxyphenyl acetic acid, aldose reductase inhibitors.
Journal of Antibiotics (1995), 48(11), 1345-6.
5
Hayashi, Ken-ichiro; Suzuki, Kiyokazu; Kawaguchi, Maki; Nakajima, Tomoko; Suzuki, Tadao; Numata, Masahiro; Nakamura, Toyoo.
Isolation of an antioxidant from Penicillium roquefortii IFO 5956.
Bioscience, Biotechnology, and Biochemistry (1995), 59(2), 319-20.
4
Hayashi, Ken-Ichiro; Nakagawa, Mashira; Fujita, Tomoyuki; Tanimori, Shinji; Nakayama, Mitsuru.
Nisamycin, a new manumycin group antibiotic from Streptomyces sp. K106. II. Structure determination and structure-activity relationships.
Journal of Antibiotics (1994), 47(10), 1110-15.
3
Nisamycin, a new manumycin group antibiotic from Streptomyces sp. K106. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties.
Hayashi, Ken-Ichiro; Nakagawa, Masahira; Nakayama, Mitsuru.
Journal of Antibiotics (1994), 47(10), 1104-9.
2
Absolute stereochemistry of alisamycin.
Hayashi, Ken-ichiro; Nakagawa, Masahira; Fujita, Tomoyuki; Nakayama, Mitsuru.
Bioscience, Biotechnology, and Biochemistry (1994), 58(7), 1332-3.
1
Nisamycin, a new manumycin group antibiotic from Streptomyces sp. K106.,
Hayashi K, Nakagawa M, Fujita T, Tanimori S and Nakayama M
Journal of Antibiotics, 1993, 46 (12): 1904-7